Every year in Australia there are around 950 new children diagnosed with cancer. To improve the outcomes of children with cancer, the Children’s Cancer Institute (CCI) initiated the Zero Childhood Cancer national personalised medicine trial (PRISM). This trial aims to match patients to the optimal treatment guided by molecular tumour profiling, high-throughput in vitro drug testing on patient-derived model systems and in vivo drug validation in patient-derived xenograft models. The Bioinformatics group at CCI plays a crucial role in unravelling and understanding the molecular basis and drivers of a child’s tumour and is essential for the integrative analyses to link molecular profiling data to in vitro generated drug efficacy data for drug hit calling and prioritisation for individual PRISM patients and the identification of novel biomarker-drug efficacy associations for future patients.
As a key partner of the Zero Childhood Cancer program, the Translational Tumour Biology (TTB) group at CCI is deeply involved in the molecular profiling and drug analysis of the program and focusses on further understanding how altered genes drive cancer and on how to translate this knowledge into new clinically applicable treatment interventions. The TTB group believes that understanding the molecular mechanisms used by cancer driver genes is the key to more effective therapies with reduced toxicity.
Currently, we are looking for a strong and creative programmer with an eye for detail and a passion for biological research to:
The bioinformatician will be embedded within the Translational Tumour Biology research group, while strongly interacting with and being fully supported by the Bioinformatics group. This unique position not only offers the opportunity for the candidate to develop new analysis approaches and make new informatic discoveries, but also to create own research questions.
Responsibilities will include, but are not limited to:
Qualifications, experience and skills required:
This is an excellent opportunity to work in an inspiring workplace. You'll be rewarded with a friendly and professional flexible work environment, comprehensive on-campus facilities, competitive salary, salary packaging options, access to a leading EAP program and regular social activities. Join a group of dedicated people in a performance-driven environment to achieve success and discover what it's like to look forward to coming to work every day and make a real difference. We're looking for people who share our values of accountability, integrity and camaraderie, teamwork, sharing and excellence, success and satisfaction.
A detailed job description and additional information about Children's Cancer Institute can be found on our website at: www.childrenscancerinstitute.org.au.
We embrace diversity and encourage applications from people from diverse backgrounds and cultures. To apply, please click the 'APPLY' link and forward both your resume AND cover letter clearly addressing the qualifications, experience and skills required. Note: Applications will be reviewed prior to the closing date; which is dependent on the status of the recruitment process.
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